LUPUS ERITEMATOSO

DERMATOLOGO UNIVERSITARIO PROFESSORE PIETRO SANTOIANNI NAPOLI

                         Attualità negli Studi in Dermatologia             

vedi anche http://www.pietrosantoianni.net

vedi anche Research Newsin questo sito Studi immunogenetici nel lupus eritematoso

Immunogenetic studies on systemic lupus erythematosus.
Sebastiani GD, Galeazzi M.Lupus.2009 Sep;18(10):878-83. 

Understanding the pathogenesis of systemic lupus erythematosus (SLE) remains a considerable challenge. Multiple abnormalities of both the innate and adaptive immune system have been described and, furthermore, immunological dysfunction precedes clinical presentation by many years. There is a strong genetic basis to SLE, which means that genetic studies can play a key role in furthering our understanding of this disease. Because susceptibility variants are present from birth and are unaffected by the course of the disease, or by its treatment, genetic analysis is, perhaps uniquely, capable of identifying fundamental, causative, disease mechanisms. In this article, we review our SLE immunogenetic studies performed in collaboration with the European Working Party on Systemic Lupus Erythematosus. By considering the results of our research and the recent advances obtained by genome-wide associations’ studies, we can begin to understand how dysregulation at a number of key immunological steps may predispose to the development of SLE.

LUPUS ERITEMATOSO, lupus eritematoso cura, lupus eritematoso cura napoli, lupus eritematoso cure, lupus eritematoso cure nuove, lupus eritematoso cure napoli, lupus eritematoso trattamenti, lupus eritematoso trattamento, lupus eritematoso rimedi, lupus eritematoso rimedio, lupus eritematoso terapia, lupus eritematoso terapie, lupus eritematoso trattamenti napoli, lupus eritematoso trattamento napoli, lupus eritematoso terapia napoli, lupus eritematoso terapie napoli, DERMATOMIOSITE, dermatomiosite cura, dermatomiosite cura napoli, dermatomiosite cure, dermatomiosite cure nuove, dermatomiosite cure napoli, dermatomiosite terapia, dermatomiosite terapie, dermatomiosite terapia napoli, dermatomiosite terapie napoli.
Annunci
%d blogger hanno fatto clic su Mi Piace per questo: